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A novel dynamic multicellular co-culture system for studying individual blood-brain barrier cell types in brain diseases and cytotoxicity testing
Blood brain barrier (BBB) cells play key roles in the physiology and pathology of the central nervous system (CNS). BBB dysfunction is implicated in many neurodegenerative diseases, including Alzheimer’s disease (AD). The BBB consists of capillary endothelial cells, pericytes encircling the endothel...
Autores principales: | Miranda-Azpiazu, Patricia, Panagiotou, Stavros, Jose, Gin, Saha, Sikha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993789/ https://www.ncbi.nlm.nih.gov/pubmed/29884831 http://dx.doi.org/10.1038/s41598-018-26480-8 |
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