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Macrophage migration inhibitory factor is required for NLRP3 inflammasome activation

Macrophage migration inhibitory factor (MIF) exerts multiple effects on immune cells, as well as having functions outside the immune system. MIF can promote inflammation through the induction of other cytokines, including TNF, IL-6, and IL-1 family cytokines. Here, we show that inhibition of MIF reg...

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Detalles Bibliográficos
Autores principales: Lang, Tali, Lee, Jacinta P. W., Elgass, Kirstin, Pinar, Anita A., Tate, Michelle D., Aitken, Elizabeth H., Fan, Huapeng, Creed, Sarah J., Deen, Nadia S., Traore, Daouda A. K., Mueller, Ivo, Stanisic, Danielle, Baiwog, Francesca S., Skene, Colin, Wilce, Matthew C. J., Mansell, Ashley, Morand, Eric F., Harris, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993818/
https://www.ncbi.nlm.nih.gov/pubmed/29884801
http://dx.doi.org/10.1038/s41467-018-04581-2