Phosphorylation of glutaminase by PKCε is essential for its enzymatic activity and critically contributes to tumorigenesis

Glutamine metabolism plays an important role in cancer development and progression. Glutaminase C (GAC), the first enzyme in glutaminolysis, has emerged as an important target for cancer therapy and many studies have focused on the mechanism of enhanced GAC expression in cancer cells. However, littl...

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Detalles Bibliográficos
Autores principales: Han, Tianyu, Zhan, Weihua, Gan, Mingxi, Liu, Fanrong, Yu, Bentong, Chin, Y. Eugene, Wang, Jian-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993826/
https://www.ncbi.nlm.nih.gov/pubmed/29515166
http://dx.doi.org/10.1038/s41422-018-0021-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993826/
https://www.ncbi.nlm.nih.gov/pubmed/29515166
http://dx.doi.org/10.1038/s41422-018-0021-y

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