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Parametric mapping using spectral analysis for (11)C-PBR28 PET reveals neuroinflammation in mild cognitive impairment subjects

PURPOSE: Neuroinflammation and microglial activation play an important role in amnestic mild cognitive impairment (MCI) and Alzheimer’s disease. In this study, we investigated the spatial distribution of neuroinflammation in MCI subjects, using spectral analysis (SA) to generate parametric maps and...

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Detalles Bibliográficos
Autores principales: Fan, Zhen, Dani, Melanie, Femminella, Grazia D., Wood, Melanie, Calsolaro, Valeria, Veronese, Mattia, Turkheimer, Federico, Gentleman, Steve, Brooks, David J., Hinz, Rainer, Edison, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993844/
https://www.ncbi.nlm.nih.gov/pubmed/29523926
http://dx.doi.org/10.1007/s00259-018-3984-5