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Parametric mapping using spectral analysis for (11)C-PBR28 PET reveals neuroinflammation in mild cognitive impairment subjects
PURPOSE: Neuroinflammation and microglial activation play an important role in amnestic mild cognitive impairment (MCI) and Alzheimer’s disease. In this study, we investigated the spatial distribution of neuroinflammation in MCI subjects, using spectral analysis (SA) to generate parametric maps and...
Autores principales: | Fan, Zhen, Dani, Melanie, Femminella, Grazia D., Wood, Melanie, Calsolaro, Valeria, Veronese, Mattia, Turkheimer, Federico, Gentleman, Steve, Brooks, David J., Hinz, Rainer, Edison, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993844/ https://www.ncbi.nlm.nih.gov/pubmed/29523926 http://dx.doi.org/10.1007/s00259-018-3984-5 |
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