A Rapamycin-Activated Caspase 9-Based Suicide Gene

Engineered T cell therapies show considerable promise in the treatment of refractory malignancies. Given the ability of engineered T cells to engraft and persist for prolonged periods along with unpredicted toxicities, incorporation of a suicide gene to allow selective depletion after administration...

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Detalles Bibliográficos
Autores principales: Stavrou, Maria, Philip, Brian, Traynor-White, Charlotte, Davis, Christopher G., Onuoha, Shimobi, Cordoba, Shaun, Thomas, Simon, Pule, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993966/
https://www.ncbi.nlm.nih.gov/pubmed/29661681
http://dx.doi.org/10.1016/j.ymthe.2018.03.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993966/
https://www.ncbi.nlm.nih.gov/pubmed/29661681
http://dx.doi.org/10.1016/j.ymthe.2018.03.001

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