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CircIBTK inhibits DNA demethylation and activation of AKT signaling pathway via miR-29b in peripheral blood mononuclear cells in systemic lupus erythematosus

BACKGROUND: Systemic lupus erythematosus (SLE) is a chronic and incurable autoimmune disease involving the dysfunction of lymphocytes. Circular RNAs (circRNAs) are noncoding RNAs (ncRNAs) with a covalently closed loop structure, with abnormal expression in various human diseases may participate in t...

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Detalles Bibliográficos
Autores principales: Wang, Xin, Zhang, Chengzhong, Wu, Zhouwei, Chen, Yue, Shi, Weimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993996/
https://www.ncbi.nlm.nih.gov/pubmed/29884225
http://dx.doi.org/10.1186/s13075-018-1618-8