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MiR-218 regulates epithelial–mesenchymal transition and angiogenesis in colorectal cancer via targeting CTGF

BACKGROUND: Endothelial-to-mesenchymal transition (EMT) and angiogenesis play important roles in colorectal cancer (CRC) development. Connective tissue growth factor (CTGF) has been reported to promote several kinds of cancer progression and miR-218 has been identified as a tumor suppressor miRNA. H...

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Detalles Bibliográficos
Autores principales: Lun, Weijian, Wu, Xiongjian, Deng, Qiliang, Zhi, Fachao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994014/
https://www.ncbi.nlm.nih.gov/pubmed/29977158
http://dx.doi.org/10.1186/s12935-018-0575-2