Calpain inhibition attenuates bleomycin-induced pulmonary fibrosis via switching the development of epithelial-mesenchymal transition

Calpains are intracellular calcium-dependent cysteine proteases, which cleave several substrates proteins, have been proven to play important roles in lung fibrosis. The aim of this study was to investigate the effects of calpain on bleomycin (BLM)-induced pulmonary fibrosis. A lung fibrosis mice mo...

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Detalles Bibliográficos
Autores principales: Liu, Yuan, Liu, Bing, Zhang, Gu-qin, Zou, Jing-feng, Zou, Meng-lin, Cheng, Zhen-shun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994212/
https://www.ncbi.nlm.nih.gov/pubmed/29666896
http://dx.doi.org/10.1007/s00210-018-1499-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994212/
https://www.ncbi.nlm.nih.gov/pubmed/29666896
http://dx.doi.org/10.1007/s00210-018-1499-z

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