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Enriched Expression of Neutral Sphingomyelinase 2 in the Striatum is Essential for Regulation of Lipid Raft Content and Motor Coordination
Sphingomyelinases are a family of enzymes that hydrolyze sphingomyelin to generate phosphocholine and ceramide. The brain distribution and function of neutral sphingomyelinase 2 (nSMase2) were elucidated in this study. nSMase2 mRNA expression was greatest in the striatum, followed by the prefrontal...
Autores principales: | Tan, Laura Hui-Ru, Tan, Angela Jin-Rong, Ng, Yu-Ying, Chua, John Jia-En, Chew, Wee-Siong, Muralidharan, Sneha, Torta, Federico, Dutta, Bamaprasad, Sze, Siu Kwan, Herr, Deron R., Ong, Wei-Yi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994222/ https://www.ncbi.nlm.nih.gov/pubmed/29043558 http://dx.doi.org/10.1007/s12035-017-0784-z |
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