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Involvement of NADPH Oxidase 1 in Liver Kinase B1-Mediated Effects on Tumor Angiogenesis and Growth

The liver kinase B1 (LKB1) gene is a tumor suppressor with an established role in the control of cell metabolism and oxidative stress. However, whether dis-regulated oxidative stress promotes growth of LKB1-deficient tumors remains substantially unknown. Through in vitro studies, we observed that lo...

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Detalles Bibliográficos
Autores principales: Zulato, Elisabetta, Ciccarese, Francesco, Nardo, Giorgia, Pinazza, Marica, Agnusdei, Valentina, Silic-Benussi, Micol, Ciminale, Vincenzo, Indraccolo, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994402/
https://www.ncbi.nlm.nih.gov/pubmed/29915721
http://dx.doi.org/10.3389/fonc.2018.00195