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Identification of a Novel EF-Loop in the N-terminus of TRPM2 Channel Involved in Calcium Sensitivity

As an oxidative stress sensor, transient receptor potential melastatin 2 (TRPM2) channel is involved in many physiological and pathological processes including warmth sensing, ischemia injury, inflammatory diseases and diabetes. Intracellular calcium is critical for TRPM2 channel activation and the...

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Detalles Bibliográficos
Autores principales: Luo, Yuhuan, Yu, Xiafei, Ma, Cheng, Luo, Jianhong, Yang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994415/
https://www.ncbi.nlm.nih.gov/pubmed/29915540
http://dx.doi.org/10.3389/fphar.2018.00581