Matrix Metalloproteinase-9-Generated COOH-, but Not NH(2)-Terminal Fragments of Serum Amyloid A1 Retain Potentiating Activity in Neutrophil Migration to CXCL8, With Loss of Direct Chemotactic and Cytokine-Inducing Capacity

Serum amyloid A1 (SAA1) is a prototypic acute phase protein, induced to extremely high levels by physical insults, including inflammation and infection. Human SAA and its NH(2)-terminal part have been studied extensively in the context of amyloidosis. By contrast, little is known about COOH-terminal...

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Detalles Bibliográficos
Autores principales: Gouwy, Mieke, De Buck, Mieke, Abouelasrar Salama, Sara, Vandooren, Jennifer, Knoops, Sofie, Pörtner, Noëmie, Vanbrabant, Lotte, Berghmans, Nele, Opdenakker, Ghislain, Proost, Paul, Van Damme, Jo, Struyf, Sofie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994419/
https://www.ncbi.nlm.nih.gov/pubmed/29915572
http://dx.doi.org/10.3389/fimmu.2018.01081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994419/
https://www.ncbi.nlm.nih.gov/pubmed/29915572
http://dx.doi.org/10.3389/fimmu.2018.01081

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