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Mitochondrial Delivery of Phenol Substructure Triggers Mitochondrial Depolarization and Apoptosis of Cancer Cells

Antitumor chemotherapy remains one of the most important challenge of the medicinal chemistry. Emerging research in chemotherapy is focused on exploiting the biochemical differences between cancer cell and normal cell metabolism in order to reduce the side effects and increase antitumor therapy effi...

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Detalles Bibliográficos
Autores principales: Gazzano, Elena, Lazzarato, Loretta, Rolando, Barbara, Kopecka, Joanna, Guglielmo, Stefano, Costamagna, Costanzo, Chegaev, Konstantin, Riganti, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994430/
https://www.ncbi.nlm.nih.gov/pubmed/29915539
http://dx.doi.org/10.3389/fphar.2018.00580