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Clinical Benefits and Cost-Effectiveness of Laboratory Monitoring Strategies to Guide Antiretroviral Treatment Switching in India

Current Indian guidelines recommend twice-annual CD4 testing to monitor first-line antiretroviral therapy (ART), with a plasma HIV RNA test to confirm failure if CD4 declines, which would prompt a switch to second-line ART. We used a mathematical model to assess the clinical benefits and cost-effect...

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Detalles Bibliográficos
Autores principales: Freedberg, Kenneth A., Kumarasamy, Nagalingeswaran, Borre, Ethan D., Ross, Eric L., Mayer, Kenneth H., Losina, Elena, Swaminathan, Soumya, Flanigan, Timothy P., Walensky, Rochelle P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994680/
https://www.ncbi.nlm.nih.gov/pubmed/29620932
http://dx.doi.org/10.1089/aid.2017.0258