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Molecular signature of Epstein-Barr virus infection in MS brain lesions

OBJECTIVE: We sought to confirm the presence and frequency of B cells and Epstein-Barr virus (EBV) (latent and lytic phase) antigens in archived MS and non-MS brain tissue by immunohistochemistry. METHODS: We quantified the type and location of B-cell subsets within active and chronic MS brain lesio...

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Detalles Bibliográficos
Autores principales: Moreno, Monica A., Or-Geva, Noga, Aftab, Blake T., Khanna, Rajiv, Croze, Ed, Steinman, Lawrence, Han, May H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994704/
https://www.ncbi.nlm.nih.gov/pubmed/29892607
http://dx.doi.org/10.1212/NXI.0000000000000466