Cargando…

Enantioselective radical process for synthesis of chiral indolines by metalloradical alkylation of diverse C(sp(3))–H bonds

A new C–C bond formation strategy based on enantioselective radical alkylation of C(sp(3))–H bonds via Co(ii)-based metalloradical catalysis has been demonstrated for stereoselective synthesis of chiral indolines. The Co(ii)-based system enables activation of aryldiazomethanes as radical precursors...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wen, Xin, Wang, Yong, Zhang, X. Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2018
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994879/ https://www.ncbi.nlm.nih.gov/pubmed/29938039 http://dx.doi.org/10.1039/c8sc01476k

Ejemplares similares

Stereoselective radical C–H alkylation with acceptor/acceptor-substituted diazo reagents via Co(ii)-based metalloradical catalysis
por: Cui, Xin, et al.
Publicado: (2015)

Metalloradical activation of α-formyldiazoacetates for the catalytic asymmetric radical cyclopropanation of alkenes
por: Xu, Xue, et al.
Publicado: (2017)

An iron(ii)-based metalloradical system for intramolecular amination of C(sp(2))–H and C(sp(3))–H bonds: synthetic applications and mechanistic studies
por: Das, Sandip Kumar, et al.
Publicado: (2022)

Synthesis of chiral N-phosphoryl aziridines through enantioselective aziridination of alkenes with phosphoryl azide via Co(II)-based metalloradical catalysis
por: Tao, Jingran, et al.
Publicado: (2014)

Intramolecular 1,5-C(sp(3))–H radical amination via Co(ii)-based metalloradical catalysis for five-membered cyclic sulfamides
por: Lu, Hongjian, et al.
Publicado: (2016)

Iridium-catalyzed enantioselective olefinic C(sp(2))–H allylic alkylation
por: Sarkar, Rahul, et al.
Publicado: (2021)

Access to P-chiral phosphine oxides by enantioselective allylic alkylation of bisphenols
por: Yang, Guo-Hui, et al.
Publicado: (2019)

The debut of chiral cyclic (alkyl)(amino)carbenes (CAACs) in enantioselective catalysis
por: Pichon, Delphine, et al.
Publicado: (2019)

Correction: Iridium-catalyzed enantioselective olefinic C(sp(2))–H allylic alkylation
por: Sarkar, Rahul, et al.
Publicado: (2021)

Chiral Aminophosphines as Catalysts for Enantioselective Double-Michael Indoline Syntheses
por: Khong, San N., et al.
Publicado: (2012)

Chiral cis-iron(ii) complexes with metal- and ligand-centered chirality for highly regio- and enantioselective alkylation of N-heteroaromatics
por: Wei, Jinhu, et al.
Publicado: (2019)

Synthesis of chiral malonates by α-alkylation of 2,2-diphenylethyl tert-butyl malonates via enantioselective phase-transfer catalysis
por: Guo, Zhibin, et al.
Publicado: (2023)

Visible-light-induced chemo-, diastereo- and enantioselective α-C(sp(3))–H functionalization of alkyl silanes
por: Feng, Lili, et al.
Publicado: (2023)

Catalytic enantioselective synthesis of macrodiolides and their application in chiral recognition
por: Xiao, Wanlong, et al.
Publicado: (2020)

Chiral Fe(ii) complex catalyzed enantioselective [1,3] O-to-C rearrangement of alkyl vinyl ethers and synthesis of chromanols and beyond
por: Wang, Lifeng, et al.
Publicado: (2020)

Recent developments for intermolecular enantioselective amination of non-acidic C(sp(3))–H bonds
por: Li, Heng-Hui, et al.
Publicado: (2023)

Metal-free direct alkylation of unfunctionalized allylic/benzylic sp(3) C–H bonds via photoredox induced radical cation deprotonation
por: Zhou, Rong, et al.
Publicado: (2017)

Enantioselective cyanation via radical-mediated C–C single bond cleavage for synthesis of chiral dinitriles
por: Wang, Tao, et al.
Publicado: (2019)

Chiral bifunctional organocatalysts for enantioselective synthesis of 3-substituted isoindolinones
por: Hu, Xiao-Mu, et al.
Publicado: (2023)

Chiral phosphoric acid-catalyzed enantioselective construction of structurally diverse benzothiazolopyrimidines
por: Jarrige, Lucie, et al.
Publicado: (2019)

Enantioselective synthesis of hydantoins by chiral acid-catalysed condensation of glyoxals and ureas
por: Aryal, Sushant, et al.
Publicado: (2023)

Hydroxy-directed iridium-catalyzed enantioselective formal β-C(sp(2))–H allylic alkylation of α,β-unsaturated carbonyls
por: Mitra, Sankash, et al.
Publicado: (2022)

Highly Diastereo- and Enantioselective CuH-Catalyzed Synthesis of 2,3-Disubstituted Indolines
por: Ascic, Erhad, et al.
Publicado: (2015)

Stability and C–H Bond Activation Reactions of Palladium(I) and Platinum(I) Metalloradicals: Carbon-to-Metal H-Atom Transfer and an Organometallic Radical Rebound Mechanism
por: Krämer, Tobias, et al.
Publicado: (2023)

Catalytic photochemical enantioselective α-alkylation with pyridinium salts
por: Yetra, Santhivardhana Reddy, et al.
Publicado: (2022)

Enantioselective one-pot synthesis of 4H-chromene derivatives catalyzed by a chiral Ni(ii) complex
por: Yu, Xuan, et al.
Publicado: (2020)

Enantioselective synthesis of chiral porphyrin macrocyclic hosts and kinetic enantiorecognition of viologen guests
por: Gilissen, Pieter J., et al.
Publicado: (2021)

Organocatalytic intramolecular (4 + 2) annulation of enals with ynamides: atroposelective synthesis of axially chiral 7-aryl indolines
por: Zhang, Zhi-Xin, et al.
Publicado: (2023)

Enantioselective synthesis of gem-disubstituted N-Boc diazaheterocycles via decarboxylative asymmetric allylic alkylation
por: Sun, Alexander W., et al.
Publicado: (2018)

Selective Iron Catalyzed Synthesis of N‐Alkylated Indolines and Indoles
por: Wu, Jiajun, et al.
Publicado: (2022)

1-Alkyl-3-alkylindolin-2-imine hydrochlorides as useful building blocks in the copper-catalyzed synthesis of polycyclic indoline scaffolds
por: Liu, Can, et al.
Publicado: (2019)

Enantioselective carbene insertion into the N–H bond of benzophenone imine
por: Yang, Jian, et al.
Publicado: (2019)

Allylic C(sp(3))–H alkylation via synergistic organo- and photoredox catalyzed radical addition to imines
por: Jia, Jiaqi, et al.
Publicado: (2020)

The first chiral diene-based metal–organic frameworks for highly enantioselective carbon–carbon bond formation reactions
por: Sawano, Takahiro, et al.
Publicado: (2015)

Iridium-catalyzed enantioselective direct vinylogous allylic alkylation of coumarins
por: Sarkar, Rahul, et al.
Publicado: (2018)

Multi-layer 3D chirality: its enantioselective synthesis and aggregation-induced emission
por: Zhang, Junliang, et al.
Publicado: (2020)

Enantioselective palladaelectro-catalyzed C–H olefinations and allylations for N–C axial chirality
por: Dhawa, Uttam, et al.
Publicado: (2021)

Enantioselective carbenoid insertion into C(sp(3))–H bonds
por: Santiago, J V, et al.
Publicado: (2016)

Copper-catalyzed enantioselective diyne cyclization via C(sp(2))–O bond cleavage
por: Zhou, Ji-Jia, et al.
Publicado: (2023)

Thiahelicene-based inherently chiral films for enantioselective electroanalysis
por: Arnaboldi, Serena, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_t9k224mhp4v95cn4mprgsusl97