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(111)In-labelled polymeric nanoparticles incorporating a ruthenium-based radiosensitizer for EGFR-targeted combination therapy in oesophageal cancer cells

Radiolabelled, drug-loaded nanoparticles may combine the theranostic properties of radionuclides, the controlled release of chemotherapy and cancer cell targeting. Here, we report the preparation of poly(lactic-co-glycolic acid) (PLGA) nanoparticles surface conjugated to DTPA-hEGF (DTPA = diethylene...

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Detalles Bibliográficos
Autores principales: Gill, Martin R., Menon, Jyothi U., Jarman, Paul J., Owen, Joshua, Skaripa-Koukelli, Irini, Able, Sarah, Thomas, Jim A., Carlisle, Robert, Vallis, Katherine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994990/
https://www.ncbi.nlm.nih.gov/pubmed/29808844
http://dx.doi.org/10.1039/c7nr09606b