Inhibition of prostaglandin E2 protects abdominal aortic aneurysm from expansion through regulating miR-29b-mediated fibrotic ECM expression

The risk of rupture, the most feared clinical consequence of abdominal aortic aneurysm, increases with the enlargement of aorta. MicroRNA-29b (miR-29b) has emerged as a key modulator of extracellular matrix (ECM) homeostasis and thereby is proposed to play a crucial role in vascular remodeling. Howe...

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Detalles Bibliográficos
Autores principales: Han, Zonglin, Zhang, Tangshan, He, Yuxiang, Li, Gang, Jin, Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995085/
https://www.ncbi.nlm.nih.gov/pubmed/29896234
http://dx.doi.org/10.3892/etm.2018.6160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995085/
https://www.ncbi.nlm.nih.gov/pubmed/29896234
http://dx.doi.org/10.3892/etm.2018.6160

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