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Inhibition of prostaglandin E2 protects abdominal aortic aneurysm from expansion through regulating miR-29b-mediated fibrotic ECM expression
The risk of rupture, the most feared clinical consequence of abdominal aortic aneurysm, increases with the enlargement of aorta. MicroRNA-29b (miR-29b) has emerged as a key modulator of extracellular matrix (ECM) homeostasis and thereby is proposed to play a crucial role in vascular remodeling. Howe...
Autores principales: | Han, Zonglin, Zhang, Tangshan, He, Yuxiang, Li, Gang, Jin, Xing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995085/ https://www.ncbi.nlm.nih.gov/pubmed/29896234 http://dx.doi.org/10.3892/etm.2018.6160 |
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