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Direct Conversion of Mouse Fibroblasts into Cholangiocyte Progenitor Cells
Disorders of the biliary epithelium, known as cholangiopathies, cause severe and irreversible liver diseases. The limited accessibility of bile duct precludes modeling of several cholangiocyte-mediated diseases. Therefore, novel approaches for obtaining functional cholangiocytes with high purity are...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995161/ https://www.ncbi.nlm.nih.gov/pubmed/29606616 http://dx.doi.org/10.1016/j.stemcr.2018.03.002 |