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Heterogeneity of Human Breast Stem and Progenitor Cells as Revealed by Transcriptional Profiling

During development, the mammary gland undergoes extensive remodeling driven by stem cells. Breast cancers are also hierarchically organized and driven by cancer stem cells characterized by CD44(+)CD24(low/−) or aldehyde dehydrogenase (ALDH) expression. These markers identify mesenchymal and epitheli...

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Detalles Bibliográficos
Autores principales: Colacino, Justin A., Azizi, Ebrahim, Brooks, Michael D., Harouaka, Ramdane, Fouladdel, Shamileh, McDermott, Sean P., Lee, Michael, Hill, David, Madden, Julie, Boerner, Julie, Cote, Michele L., Sartor, Maureen A., Rozek, Laura S., Wicha, Max S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995162/
https://www.ncbi.nlm.nih.gov/pubmed/29606612
http://dx.doi.org/10.1016/j.stemcr.2018.03.001