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Heterogeneity of Human Breast Stem and Progenitor Cells as Revealed by Transcriptional Profiling
During development, the mammary gland undergoes extensive remodeling driven by stem cells. Breast cancers are also hierarchically organized and driven by cancer stem cells characterized by CD44(+)CD24(low/−) or aldehyde dehydrogenase (ALDH) expression. These markers identify mesenchymal and epitheli...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995162/ https://www.ncbi.nlm.nih.gov/pubmed/29606612 http://dx.doi.org/10.1016/j.stemcr.2018.03.001 |