PSMD4 is a novel therapeutic target in chemoresistant colorectal cancer activated by cytoplasmic localization of Nrf2

Nuclear Nrf2 (nNrf2) binding to the antioxidant response element may promote chemoresistance in colorectal cancer. However, the shuttling of Nrf2 between cytoplasm and nucleus in colon cancer cells has revealed the possibility that cytoplasmic location of Nrf2 (cNrf2) may play a specific role in che...

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Detalles Bibliográficos
Autores principales: Cheng, Ya-Min, Lin, Po-Lin, Wu, De-Wei, Wang, Lee, Huang, Chi-Chou, Lee, Huei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995171/
https://www.ncbi.nlm.nih.gov/pubmed/29899863
http://dx.doi.org/10.18632/oncotarget.25254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995171/
https://www.ncbi.nlm.nih.gov/pubmed/29899863
http://dx.doi.org/10.18632/oncotarget.25254

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