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PSMD4 is a novel therapeutic target in chemoresistant colorectal cancer activated by cytoplasmic localization of Nrf2
Nuclear Nrf2 (nNrf2) binding to the antioxidant response element may promote chemoresistance in colorectal cancer. However, the shuttling of Nrf2 between cytoplasm and nucleus in colon cancer cells has revealed the possibility that cytoplasmic location of Nrf2 (cNrf2) may play a specific role in che...
Autores principales: | Cheng, Ya-Min, Lin, Po-Lin, Wu, De-Wei, Wang, Lee, Huang, Chi-Chou, Lee, Huei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995171/ https://www.ncbi.nlm.nih.gov/pubmed/29899863 http://dx.doi.org/10.18632/oncotarget.25254 |
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