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Distinct age-associated molecular profiles in acute myeloid leukemia defined by comprehensive clinical genomic profiling

Large scale comprehensive genomic profiling (CGP) has led to an improved understanding of oncogenic mutations in acute myeloid leukemia (AML), as well as identification of alterations that can serve as targets for potential therapeutic intervention. We sought to gain insight into age-associated vari...

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Detalles Bibliográficos
Autores principales: Tarlock, Katherine, Zhong, Shan, He, Yuting, Ries, Rhonda, Severson, Eric, Bailey, Mark, Morley, Samantha, Balasubramanian, Sohail, Erlich, Rachel, Lipson, Doron, Otto, Geoff A., Vergillo, Jo-Anne, Kolb, E. Anders, Ross, Jeffrey S., Mughal, Tariq, Stephens, Philip J., Miller, Vincent, Meshinchi, Soheil, He, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995178/
https://www.ncbi.nlm.nih.gov/pubmed/29899868
http://dx.doi.org/10.18632/oncotarget.25443