Oleanolic acid induces p53-dependent apoptosis via the ERK/JNK/AKT pathway in cancer cell lines in prostatic cancer xenografts in mice

We evaluated oleanolic acid (OA)-induced anti-cancer activity, apoptotic mechanism, cell cycle status, and MAPK kinase signaling in DU145 (prostate cancer), MCF-7 (breast cancer), U87 (human glioblastoma), normal murine liver cell (BNL CL.2) and human foreskin fibroblast cell lines (Hs 68). The IC50...

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Detalles Bibliográficos
Autores principales: Kim, Gyeong-Ji, Jo, Hyeon-Ju, Lee, Kwon-Jai, Choi, Jeong Woo, An, Jeung Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995180/
https://www.ncbi.nlm.nih.gov/pubmed/29899865
http://dx.doi.org/10.18632/oncotarget.25316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995180/
https://www.ncbi.nlm.nih.gov/pubmed/29899865
http://dx.doi.org/10.18632/oncotarget.25316

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