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Alignment Modulates Ancestral Sequence Reconstruction Accuracy
Accurate reconstruction of ancestral states is a critical evolutionary analysis when studying ancient proteins and comparing biochemical properties between parental or extinct species and their extant relatives. It relies on multiple sequence alignment (MSA) which may introduce biases, and it remain...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995191/ https://www.ncbi.nlm.nih.gov/pubmed/29618097 http://dx.doi.org/10.1093/molbev/msy055 |