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Alignment Modulates Ancestral Sequence Reconstruction Accuracy

Accurate reconstruction of ancestral states is a critical evolutionary analysis when studying ancient proteins and comparing biochemical properties between parental or extinct species and their extant relatives. It relies on multiple sequence alignment (MSA) which may introduce biases, and it remain...

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Detalles Bibliográficos
Autores principales:	Vialle, Ricardo Assunção, Tamuri, Asif U, Goldman, Nick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Methods
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995191/ https://www.ncbi.nlm.nih.gov/pubmed/29618097 http://dx.doi.org/10.1093/molbev/msy055

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