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DNA silencing by prokaryotic Argonaute proteins adds a new layer of defense against invading nucleic acids

Argonaute (Ago) proteins are encoded in all three domains of life and are responsible for the regulation of intracellular nucleic acid levels. Whereas some Ago variants are able to cleave target nucleic acids by their endonucleolytic activity, others only bind to their target nucleic acids while tar...

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Detalles Bibliográficos
Autores principales: Willkomm, Sarah, Makarova, Kira S, Grohmann, Dina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995195/
https://www.ncbi.nlm.nih.gov/pubmed/29579258
http://dx.doi.org/10.1093/femsre/fuy010