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DNA silencing by prokaryotic Argonaute proteins adds a new layer of defense against invading nucleic acids
Argonaute (Ago) proteins are encoded in all three domains of life and are responsible for the regulation of intracellular nucleic acid levels. Whereas some Ago variants are able to cleave target nucleic acids by their endonucleolytic activity, others only bind to their target nucleic acids while tar...
Autores principales: | Willkomm, Sarah, Makarova, Kira S, Grohmann, Dina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995195/ https://www.ncbi.nlm.nih.gov/pubmed/29579258 http://dx.doi.org/10.1093/femsre/fuy010 |
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