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Translation termination-dependent deadenylation of MYC mRNA in human cells

The earliest step in the mRNA degradation process is deadenylation, a progressive shortening of the mRNA poly(A) tail by deadenylases. The question of when deadenylation takes place remains open. MYC mRNA is one of the rare examples for which it was proposed a shortening of the poly(A) tail during o...

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Detalles Bibliográficos
Autores principales: Jolles, Béatrice, Aliouat, Affaf, Stierlé, Vérène, Salhi, Samia, Jean-Jean, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995228/
https://www.ncbi.nlm.nih.gov/pubmed/29899850
http://dx.doi.org/10.18632/oncotarget.25459