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Development of a preclinical humanized mouse model to evaluate acute toxicity of an influenza vaccine
Safety evaluation of a human vaccine is critical for vaccine development and for preventing an unexpected adverse reaction in humans. Nonetheless, to date, very few systems have been described for preclinical studies of human adverse reactions in vivo. Previously, we have identified biomarker genes...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995229/ https://www.ncbi.nlm.nih.gov/pubmed/29899819 http://dx.doi.org/10.18632/oncotarget.25399 |