Targeting the SET and RING-associated (SRA) domain of ubiquitin-like, PHD and ring finger–containing 1 (UHRF1) for anti-cancer drug development

Ubiquitin-like containing PHD Ring Finger 1 (UHRF1) is a multi-domain protein with a methyl-DNA binding SRA (SET and RING-associated) domain, required for maintenance DNA methylation mediated by DNMT1. Primarily expressed in proliferating cells, UHRF1 is a cell-cycle regulated protein that is requir...

Descripción completa

Detalles Bibliográficos
Autores principales: Patnaik, Debasis, Estève, Pierre-Olivier, Pradhan, Sriharsa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995235/
https://www.ncbi.nlm.nih.gov/pubmed/29899856
http://dx.doi.org/10.18632/oncotarget.25425

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995235/
https://www.ncbi.nlm.nih.gov/pubmed/29899856
http://dx.doi.org/10.18632/oncotarget.25425

Ejemplares similares