Metformin exerts antitumor activity via induction of multiple death pathways in tumor cells and activation of a protective immune response

The antitumor effect of metformin has been demonstrated in several types of cancer; however, the mechanisms involved are incompletely understood. In this study, we showed that metformin acts directly on melanoma cells as well as on the tumor microenvironment, particularly in the context of the immun...

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Detalles Bibliográficos
Autores principales: Pereira, Felipe V., Melo, Amanda Campelo L., Low, Jun Siong, de Castro, Íris Arantes, Braga, Tárcio T., Almeida, Danilo C., Batista de Lima, Ana Gabriela U., Hiyane, Meire I., Correa-Costa, Matheus, Andrade-Oliveira, Vinicius, Origassa, Clarice S.T., Pereira, Rosana M., Kaech, Susan M., Rodrigues, Elaine G., Câmara, Niels Olsen S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995253/
https://www.ncbi.nlm.nih.gov/pubmed/29899823
http://dx.doi.org/10.18632/oncotarget.25380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995253/
https://www.ncbi.nlm.nih.gov/pubmed/29899823
http://dx.doi.org/10.18632/oncotarget.25380

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