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Targeted DNA sequencing of non-small cell lung cancer identifies mutations associated with brain metastases

INTRODUCTION: This study explores the hypothesis that dominant molecular oncogenes in non-small cell lung cancer (NSCLC) are associated with metastatic spread to the brain. METHODS: NSCLC patient groups with no evidence of metastasis, with metastatic disease to a non-CNS site, who developed brain me...

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Detalles Bibliográficos
Autores principales: Wilson, George D., Johnson, Matthew D., Ahmed, Samreen, Cardenas, Paola Yumpo, Grills, Inga S., Thibodeau, Bryan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995256/
https://www.ncbi.nlm.nih.gov/pubmed/29899834
http://dx.doi.org/10.18632/oncotarget.25409