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Matched Developmental Timing of Donor Cells with the Host Is Crucial for Chimera Formation
Chimeric mice have been generated by injecting pluripotent stem cells into morula-to-blastocyst stage mouse embryo or by introducing more mature cells into later stage embryos that correspond to the differentiation stage of the donor cells. It has not been rigorously tested, however, whether success...
Autores principales: | Cohen, Malkiel A., Markoulaki, Styliani, Jaenisch, Rudolf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995271/ https://www.ncbi.nlm.nih.gov/pubmed/29606614 http://dx.doi.org/10.1016/j.stemcr.2018.03.004 |
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