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In Vivo Genetic Manipulation of Spermatogonial Stem Cells and Their Microenvironment by Adeno-Associated Viruses

Adeno-associated virus (AAV) penetrates the blood-brain barrier, but it is unknown whether AAV penetrates other tight junctions. Genetic manipulation of testis has been hampered by the basement membrane of seminiferous tubules and the blood-testis barrier (BTB), which forms between Sertoli cells and...

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Detalles Bibliográficos
Autores principales: Watanabe, Satoshi, Kanatsu-Shinohara, Mito, Ogonuki, Narumi, Matoba, Shogo, Ogura, Atsuo, Shinohara, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995272/
https://www.ncbi.nlm.nih.gov/pubmed/29628393
http://dx.doi.org/10.1016/j.stemcr.2018.03.005