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In Vivo Genetic Manipulation of Spermatogonial Stem Cells and Their Microenvironment by Adeno-Associated Viruses
Adeno-associated virus (AAV) penetrates the blood-brain barrier, but it is unknown whether AAV penetrates other tight junctions. Genetic manipulation of testis has been hampered by the basement membrane of seminiferous tubules and the blood-testis barrier (BTB), which forms between Sertoli cells and...
Autores principales: | Watanabe, Satoshi, Kanatsu-Shinohara, Mito, Ogonuki, Narumi, Matoba, Shogo, Ogura, Atsuo, Shinohara, Takashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995272/ https://www.ncbi.nlm.nih.gov/pubmed/29628393 http://dx.doi.org/10.1016/j.stemcr.2018.03.005 |
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