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Influence of TS (rs34743033) and RUNX1 (rs2014300) gene polymorphisms on survival outcomes of fluorouracil-based chemotherapy in Chinese advanced gastric cancer patients

BACKGROUND: This study aimed to explore the clinical correlation of single-nucleotide polymorphisms of thymidylate synthase (TS) and runt-related transcription factor 1 (RUNX1) in patients with postoperative stage II and III gastric cancer (GC). PATIENTS AND METHODS: Samples were obtained from 661 p...

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Detalles Bibliográficos
Autores principales: Han, Rongbo, Wei, Jingsun, Zhang, Honghong, Su, Xinyu, Chu, Xia, Chen, Yuetong, Gong, Yang, Wang, Xiujuan, Shi, Junfeng, Chen, Jinfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995278/
https://www.ncbi.nlm.nih.gov/pubmed/29922087
http://dx.doi.org/10.2147/CMAR.S158647