Diltiazem improves contractile properties of skeletal muscle in dysferlin‐deficient BLAJ mice, but does not reduce contraction‐induced muscle damage

B6.A‐Dysf (prmd)/GeneJ (BLAJ) mice model human limb‐girdle muscular dystrophy 2B (LGMD2B), which is linked to mutations in the dysferlin (DYSF) gene. We tested the hypothesis that, the calcium ion (Ca(2+)) channel blocker diltiazem (DTZ), reduces contraction‐induced skeletal muscle damage, in BLAJ m...

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Detalles Bibliográficos
Autores principales: Begam, Morium, Collier, Alyssa F., Mueller, Amber L., Roche, Renuka, Galen, Sujay S., Roche, Joseph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995314/
https://www.ncbi.nlm.nih.gov/pubmed/29890050
http://dx.doi.org/10.14814/phy2.13727

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995314/
https://www.ncbi.nlm.nih.gov/pubmed/29890050
http://dx.doi.org/10.14814/phy2.13727

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