Differential role of GPR142 in tryptophan-mediated enhancement of insulin secretion in obese and lean mice

Tryptophan is reportedly the most potent agonist for GPR142. Glucose-stimulated insulin secretion (GSIS) from pancreatic beta cells are enhanced by GPR142-mediated signal. It is not clear, however, if GPR142-mediated signals is solely attributable to GSIS enhancement after tryptophan load in various...

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Detalles Bibliográficos
Autores principales: Ueda, Yoko, Iwakura, Hiroshi, Bando, Mika, Doi, Asako, Ariyasu, Hiroyuki, Inaba, Hidefumi, Morita, Shuhei, Akamizu, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995358/
https://www.ncbi.nlm.nih.gov/pubmed/29889885
http://dx.doi.org/10.1371/journal.pone.0198762

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995358/
https://www.ncbi.nlm.nih.gov/pubmed/29889885
http://dx.doi.org/10.1371/journal.pone.0198762

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