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X Chromosome Dosage Influences DNA Methylation Dynamics during Reprogramming to Mouse iPSCs
A dramatic difference in global DNA methylation between male and female cells characterizes mouse embryonic stem cells (ESCs), unlike somatic cells. We analyzed DNA methylation changes during reprogramming of male and female somatic cells and in resulting induced pluripotent stem cells (iPSCs). At a...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995367/ https://www.ncbi.nlm.nih.gov/pubmed/29681539 http://dx.doi.org/10.1016/j.stemcr.2018.03.019 |