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Predicting human protein function with multi-task deep neural networks

Machine learning methods for protein function prediction are urgently needed, especially now that a substantial fraction of known sequences remains unannotated despite the extensive use of functional assignments based on sequence similarity. One major bottleneck supervised learning faces in protein...

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Detalles Bibliográficos
Autores principales: Fa, Rui, Cozzetto, Domenico, Wan, Cen, Jones, David T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995439/
https://www.ncbi.nlm.nih.gov/pubmed/29889900
http://dx.doi.org/10.1371/journal.pone.0198216