CXCL12/CXCR4 Signaling Enhances Human PSC-Derived Hematopoietic Progenitor Function and Overcomes Early In Vivo Transplantation Failure

Human pluripotent stem cells (hPSCs) generate hematopoietic progenitor cells (HPCs) but fail to engraft xenograft models used to detect adult/somatic hematopoietic stem cells (HSCs) from donors. Recent progress to derive hPSC-derived HSCs has relied on cell-autonomous forced expression of transcript...

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Detalles Bibliográficos
Autores principales: Reid, Jennifer C., Tanasijevic, Borko, Golubeva, Diana, Boyd, Allison L., Porras, Deanna P., Collins, Tony J., Bhatia, Mickie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995456/
https://www.ncbi.nlm.nih.gov/pubmed/29742393
http://dx.doi.org/10.1016/j.stemcr.2018.04.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995456/
https://www.ncbi.nlm.nih.gov/pubmed/29742393
http://dx.doi.org/10.1016/j.stemcr.2018.04.003

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