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Spatial Patterns and Age-Related Changes of the Collagen Crimp in the Human Cornea and Sclera

PURPOSE: Collagen is the main load-bearing component of the eye, and collagen crimp is a critical determinant of tissue mechanical behavior. We test the hypothesis that collagen crimp morphology varies over the human cornea and sclera and with age. METHODS: We analyzed 42 axial whole-globe sections...

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Detalles Bibliográficos
Autores principales: Gogola, Alexandra, Jan, Ning-Jiun, Brazile, Bryn, Lam, Po, Lathrop, Kira L., Chan, Kevin C., Sigal, Ian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995484/
https://www.ncbi.nlm.nih.gov/pubmed/30025116
http://dx.doi.org/10.1167/iovs.17-23474