Pharmacokinetics of the Oral Selective CXCR2 Antagonist AZD5069: A Summary of Eight Phase I Studies in Healthy Volunteers

OBJECTIVE: The aim of this study was to summarise the pharmacokinetic findings from eight phase I studies in healthy volunteers given oral AZD5069, a selective small-molecule CXCR2 antagonist. METHODS: 240 healthy volunteers across eight phase I studies received single (0.1–200 mg) or multiple once-...

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Detalles Bibliográficos
Autores principales: Cullberg, Marie, Arfvidsson, Cecilia, Larsson, Bengt, Malmgren, Anna, Mitchell, Patrick, Wählby Hamrén, Ulrika, Wray, Heather
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995788/
https://www.ncbi.nlm.nih.gov/pubmed/29856004
http://dx.doi.org/10.1007/s40268-018-0236-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995788/
https://www.ncbi.nlm.nih.gov/pubmed/29856004
http://dx.doi.org/10.1007/s40268-018-0236-x

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