Co-crystal of Tramadol–Celecoxib in Patients with Moderate to Severe Acute Post-surgical Oral Pain: A Dose-Finding, Randomised, Double-Blind, Placebo- and Active-Controlled, Multicentre, Phase II Trial

BACKGROUND: Co-crystal of tramadol–celecoxib (CTC), containing equimolar quantities of the active pharmaceutical ingredients (APIs) tramadol and celecoxib (100 mg CTC = 44 mg rac–tramadol hydrochloride and 56 mg celecoxib), is a novel API-API co-crystal for the treatment of pain. We aimed to establi...

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Detalles Bibliográficos
Autores principales: López-Cedrún, José, Videla, Sebastián, Burgueño, Miguel, Juárez, Inma, Aboul-Hosn, Samir, Martín-Granizo, Rafael, Grau, Joan, Puche, Miguel, Gil-Diez, José-Luis, Hueto, José-Antonio, Vaqué, Anna, Sust, Mariano, Plata-Salamán, Carlos, Monner, Antoni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995791/
https://www.ncbi.nlm.nih.gov/pubmed/29799099
http://dx.doi.org/10.1007/s40268-018-0235-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995791/
https://www.ncbi.nlm.nih.gov/pubmed/29799099
http://dx.doi.org/10.1007/s40268-018-0235-y

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