A Phase I Study of the Pharmacokinetics and Pharmacodynamics of Intranasal Doxylamine in Subjects with Chronic Intermittent Sleep Impairment

INTRODUCTION: Doxylamine tablets are approved as an over-the-counter sleep aid. We developed a doxylamine succinate intranasal metered-dose delivery system with the expectation of a more rapid onset of action with reduced side-effect potential compared with the oral tablet. METHODS: This phase I stu...

Descripción completa

Detalles Bibliográficos
Autores principales: Allison, Mark, Hale, Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995792/
https://www.ncbi.nlm.nih.gov/pubmed/29671128
http://dx.doi.org/10.1007/s40268-018-0232-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995792/
https://www.ncbi.nlm.nih.gov/pubmed/29671128
http://dx.doi.org/10.1007/s40268-018-0232-1

Ejemplares similares