Metabolomic and microarray analyses of adipose tissue of dapagliflozin-treated mice, and effects of 3-hydroxybutyrate on induction of adiponectin in adipocytes

Sodium/glucose cotransporter 2 (SGLT2) inhibitor improves systemic glucose metabolism. To clarify the effect of dapagliflozin, we performed gene expression microarray and metabolomic analyses of murine adipose tissue. Three groups of mice were used; non-diabetic control KK mice (KK), diabetic KKAy m...

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Detalles Bibliográficos
Autores principales: Nishitani, Shigeki, Fukuhara, Atsunori, Shin, Jihoon, Okuno, Yosuke, Otsuki, Michio, Shimomura, Iichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995811/
https://www.ncbi.nlm.nih.gov/pubmed/29891844
http://dx.doi.org/10.1038/s41598-018-27181-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995811/
https://www.ncbi.nlm.nih.gov/pubmed/29891844
http://dx.doi.org/10.1038/s41598-018-27181-y

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