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NF-кB increases LPS-mediated procalcitonin production in human hepatocytes

For years, procalcitonin (PCT) has been employed as a diagnostic biomarker for the severity of sepsis and septic shock, as well as for guiding the application of antibiotics. However, the molecular/cellular basis for the regulation of PCT production is not fully understood. In this study, we identif...

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Detalles Bibliográficos
Autores principales: Bai, Yongfeng, Lu, Jun, Cheng, Ying, Zhang, Feng, Fan, Xueyu, Weng, Yuanyuan, Zhu, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995812/
https://www.ncbi.nlm.nih.gov/pubmed/29891911
http://dx.doi.org/10.1038/s41598-018-27302-7